3D-PRINTED BIOACTIVE GLASS/NATURAL POLYMER SCAFFOLDS FOR APPLICATION IN BONE TISSUE ENGINEERING

Maria Eduarda Xavier da Silva; Dachamir Hotza

Todos os Trabalhos

Trabalho

Título do Trabalho

3D-PRINTED BIOACTIVE GLASS/NATURAL POLYMER SCAFFOLDS FOR APPLICATION IN BONE TISSUE ENGINEERING

Autores

Maria Eduarda Xavier da Silva
Dachamir Hotza

Modalidade

Oral Pitch and Poster

Área temática

3) Aplicações (uso de impressão 3D de materiais cerâmicos na área médica, odontológica, energia, industrial...)

Data de Publicação

05/11/2024

País da Publicação

Brasil

Idioma da Publicação

Inglês

Página do Trabalho

https://www.even3.com.br/anais/ceramicam-2024/881440-3d-printed-bioactive-glassnatural-polymer-scaffolds-for-application-in-bone-tissue-engineering

ISBN

978-65-272-1074-0

Palavras-Chave

Bioactive Glass, Natural Polymers, Biomaterials, Direct Ink Writing (DIW), Bone Tissue Engineering

Resumo

Bone tissue engineering aims to develop innovative materials that can effectively replace or regenerate damaged bone tissue. Among various approaches, additive manufacturing (AM) has garnered significant attention for its ability to mimic the complex architecture of bones. This study explores the development of scaffolds for bone tissue engineering. 3D-printing technology was used for the fabrication of scaffolds that combine the osteoinductive properties of bioglass with the biocompatibility and structural support of natural polymers, such as collagen and gelatin. These composite scaffolds are designed to mimic the bone composition, providing an optimal environment for bone regeneration. Bioglass promotes the formation of hydroxyapatite, while collagen and gelatin provide structure. By combining these materials, the scaffolds leverage of the bioactivity of bioglass and the structural and biological properties of natural polymers. The fabrication process involves AM via direct ink writing (DIW) to control scaffold architecture to support bone tissue growth. The methodology includes the selection of raw materials, preparation of the paste for AM processing, 3D-printing production, and subsequent drying. Characterization techniques such as optical microscopy (OM), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR) were employed to assess the properties of the scaffolds. This study investigates the composition and processes for obtaining bioceramic scaffolds. Overall, bioactive glass/natural polymer scaffolds can be utilized in various orthopedic and dental applications, including fracture repair, spinal fusion, and maxillofacial reconstruction. The versatility of 3D printing allows for customization of scaffold geometry to match patient-specific requirements, enhancing treatment efficacy. Additional research will optimize the biological properties of the scaffolds and explore controlled release of therapeutic agents in bone tissue engineering.

Título do Evento: CeramicAM 2024 - 1º Encontro Brasileiro de Manufatura Aditiva de Cerâmica
Cidade do Evento: São Carlos
Título dos Anais do Evento: Proceedings of the Brazilian Meeting on Ceramic Additive Manufacturing (CeramicAM Brasil)
Nome da Editora: Even3
Meio de Divulgação: Meio Digital

Como citar

SILVA, Maria Eduarda Xavier da; HOTZA, Dachamir. 3D-PRINTED BIOACTIVE GLASS/NATURAL POLYMER SCAFFOLDS FOR APPLICATION IN BONE TISSUE ENGINEERING.. In: Proceedings of the Brazilian Meeting on Ceramic Additive Manufacturing (CeramicAM Brasil). Anais...São Carlos(SP) University of São Paulo, 2024. Disponível em: https//www.even3.com.br/anais/ceramicam-2024/881440-3D-PRINTED-BIOACTIVE-GLASSNATURAL-POLYMER-SCAFFOLDS-FOR-APPLICATION-IN-BONE-TISSUE-ENGINEERING. Acesso em: 28/05/2025