Anais do Congresso Brasileiro de Virologia & Encontro de Virologia do Mercosul

DETECTION OF YELLOW FEVER VIRUS (YFV) IN THE SYLVATIC MOSQUITO PSOROPHORA (JAN.) FEROX DURING YELLOW FEVER SURVEILLANCE IN THE STATE OF SÃO PAULO, BRAZIL

Published in 04/01/2021 - ISBN: 978-65-5941-175-7

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DOI
10.29327/cbv.291763  
Paper Title
DETECTION OF YELLOW FEVER VIRUS (YFV) IN THE SYLVATIC MOSQUITO PSOROPHORA (JAN.) FEROX DURING YELLOW FEVER SURVEILLANCE IN THE STATE OF SÃO PAULO, BRAZIL
Authors
  • Karolina Morales Barrio Nuevo
  • Giovana Santos Caleiro
  • Aline Ferrari Gomes
  • Caio Santos de Souza
  • Viviana Menezes dos Santos
  • Laís Sampaio de Azevedo
  • Fernanda Gisele da Silva Vasami
  • Adriana Yurika Maeda
  • Antonio Charlys da Costa
  • Mariana Sequetin Cunha
Modality
Resumo
Subject area
Humana
Publishing Date
04/01/2021
Country of Publishing
Brasil
Language of Publishing
Inglês
Paper Page
https://www.even3.com.br/anais/cbv/291763-detection-of-yellow-fever-virus-(yfv)-in-the-sylvatic-mosquito-psorophora-(jan)-ferox-during-yellow-fever-survei
ISBN
978-65-5941-175-7
Keywords
Yellow Fever, Flavivirus, mosquitoes, outbreaks, State of São Paulo
Summary
Yellow fever (YF) is an endemic disease in some parts of Africa and America caused by Yellow Fever virus (YFV), an arbovirus of Flavivirus genus (Flaviviridae family). It is a severe disease in humans, and it may presents in its classic form a high lethal hemorrhagic fever. In Brazil, this arbovirus is maintained in two transmission cycles: the sylvatic one is maintained among non-human primates (NHP) as vertebrate hosts and transmitted by mosquitoes, such as Haemagogus-spp and Sabethes-spp, periodically causing outbreaks of Public Health impacts, and an urban cycle involving Aedes aegypti. In Brazil, the last urban outbreaks occurred in 1942, in Acre. Beginning in 2016, the Southeastern Brazilian region registered the last large sylvatic outbreak. The aim of this study was to investigate yellow fever virus in mosquitoes collected in the State of São Paulo in areas during the intense circulation of YFV between 2016 to 2018. Mosquitoes collection were carried out by SUCEN (Superintendence for Control of Endemic Diseases, State of São Paulo) in different municipalities of the State of São Paulo during the yellow fever surveillance. They were captured at ground level between 9 am and 3 pm, by using an entomologic net and bottle-type manual vacuums in woods and green areas, and Nasci’s Aspirator in urban dwellings, and identified morphologically and grouped into pools, and processed at the Vector-borne Disease Laboratory at Adolfo Lutz Institute (City of São Paulo). A total of 2,204 pools were tested for YFV by qRT-PCR. Four pools contained non-engorged females of Psorophora ferox were positive to YFV, being two pools with only one mosquito, other with two mosquitoes, and other with 14 mosquitoes (varying from Ct 31 to 38). It occurs from Southern Canada to Northern Argentina and Uruguay, being found in forested areas with dense vegetation and constant shading. Ps. ferox is resilient to changes in the environment and have occupied areas in peri-urban and urban sites. Females are zoophilic, opportunistic, persistent, voracious hematophagous, and painful biters, essentially with daytime habits. This species has previously been found naturally infected with arbovirus, such as Venezuelan Equine Encephalitis virus, in North of South America, and Brazilian Amazon, Saint Louis Encephalitis virus, in Trinidad, Mayaro and Ilheus virus, and had been incriminated as a possible vector of Rocio virus during an outbreak in the coast of São Paulo. Besides that, it has been hypothesized as a possible sylvatic YFV vector in the northwest region of State of São Paulo during epizootic events in 2008. However, no evidence of transmission associated with Ps. ferox had been verified. So, to the best of our knowledge, more studies are needed to better understand the real epidemiological importance of this specie, and studies about vector competence and capacity are required to shed light on the transmission dynamics of YFV and the potential risk of future outbreaks of YF in the region. Financial Support: São Paulo State Department of Health (SES), Brazilian Ministry of Health; Health Education and Mass Immunization Fund against Communicable Diseases (Fesima).
Title of the Event
XXXI Congresso Brasileiro de Virologia & XV Encontro de Virologia do Mercosul
Title of the Proceedings of the event
Anais do Congresso Brasileiro de Virologia & Encontro de Virologia do Mercosul
Name of the Publisher
Even3
Means of Dissemination
Meio Digital
DOI

How to cite

NUEVO, Karolina Morales Barrio et al.. DETECTION OF YELLOW FEVER VIRUS (YFV) IN THE SYLVATIC MOSQUITO PSOROPHORA (JAN.) FEROX DURING YELLOW FEVER SURVEILLANCE IN THE STATE OF SÃO PAULO, BRAZIL.. In: Congresso Brasileiro de Virologia & Encontro de Virologia do Mercosul. Anais...Porto Alegre(RS) Online, 2020. Available in: https//www.even3.com.br/anais/cbv/291763-DETECTION-OF-YELLOW-FEVER-VIRUS-(YFV)-IN-THE-SYLVATIC-MOSQUITO-PSOROPHORA-(JAN)-FEROX-DURING-YELLOW-FEVER-SURVEI. Access in: 12/09/2025

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