The IV Symposium One Health is an initiative of the Mato Grosso do Sul State Department of Health (SES/MS), through the One Health Coordination, which continues a trajectory started in 2022. Consolidated as a technical-scientific space for dialogue and innovation, the event promotes the construction of integrated solutions to health challenges at the interface between human, animal and environmental health. The fourth edition will be held on May 12 and 13, 2026, in Campo Grande (MS), with a focus on strengthening health surveillance and management in the SUS, valuing the democratization of knowledge, the participation of multiple professional profiles and traditional communities. The program will feature national and international experts and will mark the launch of the integrated digital tool MORE HEALTH PANEL – SINGLE HEALTH.