X-Meeting presentations

AEROMONAS HYDROPHILA: INSIGHTS INTO VIRULENCE AND PATHOGENICITY

Published in 08/11/2023 - ISBN: 978-65-272-0061-1

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Paper Title
AEROMONAS HYDROPHILA: INSIGHTS INTO VIRULENCE AND PATHOGENICITY
Authors
  • Rebeca Dias Serafim Corrêa
  • Marcela Laryssa Oliveira Duarte
  • Agatha Lemos Rezende Cristeli de Araujo
  • mariana silva batista
  • Juan Carlos Ariute
  • Diego Lucas Neres Rodrigues
  • Siomar de Castro Soares
  • Vasco A de C Azevedo
  • MATEUS MATIUZZI DA COSTA
  • Flávia Figueira Aburjaile
Modality
Late poster
Subject area
DNA and Genomics
Publishing Date
08/11/2023
Country of Publishing
Brazil | Brasil
Language of Publishing
en-US
Paper Page
https://www.even3.com.br/anais/xmeeting2023/648056-aeromonas-hydrophila--insights-into-virulence-and-pathogenicity
ISBN
978-65-272-0061-1
Keywords
Aeromonas hydrophila, virulence, resistance genes, pathogenicity
Summary
Aeromonas hydrophila is a Gram-negative pathogenic bacterium associated with outbreaks of septicemia in commercially valuable fish such as Nile tilapia. Besides the economic losses resulting from the high morbidity and mortality rates caused by this bacterium, risks have been described regarding the health of immunosuppressed individuals and potential risks to people who come into contact with fish infected by this bacterium. Furthermore, strains resistant to important antimicrobials have been discovered in recent years, as a consequence of indiscriminate use of antibiotics, making the control of A. hydrophila infections a major challenge and a public health alert. In this context, the present study aimed to investigate resistance and virulence genes present in this bacterium genome. The Gipsy tool was used for the study of genomic islands, using the non-pathogenic bacterium Tolumonas auensis as a reference genome. The Abricate tool was also used to find virulence and antimicrobial resistance genes. In addition, tools were used for the search of bacteriocins. Among the 35 genomes analyzed, all presented genomic islands, but according to the software, only 22 of them had a strong score, suggesting that these are more likely to provide selective advantages. The presence of genomic islands suggests that these strains may have genetically evolved and started to exhibit new genes through the process of horizontal transfer. Moreover, this study revealed the presence of important virulence and resistance genes for the survival of the pathogen. In all investigated genomes, there was at least one coding gene associated with bacteriocins. Among them, except for the genome (Ah_watGTCBM21), all genomes that present a colicin V coding gene also present a colicin I receptor coding gene. Studies also showed that the gene profile associated with bacteriocins is very similar among A. hydrophila isolates. As the next steps, the findings of this study open perspectives for future investigations into A. hydrophila. With these additional approaches, we may progress towards a more comprehensive and detailed understanding of the pathogenic characteristics of this bacterium.
Title of the Event
X-Meeting / BSB 2023
City of the Event
Curitiba
Title of the Proceedings of the event
X-Meeting presentations
Name of the Publisher
Even3
Means of Dissemination
Meio Digital

How to cite

CORRÊA, Rebeca Dias Serafim et al.. AEROMONAS HYDROPHILA: INSIGHTS INTO VIRULENCE AND PATHOGENICITY.. In: X-Meeting presentations. Anais...Curitiba(PR) Campus da indústria, 2023. Available in: https//www.even3.com.br/anais/xmeeting2023/648056-AEROMONAS-HYDROPHILA--INSIGHTS-INTO-VIRULENCE-AND-PATHOGENICITY. Access in: 10/06/2026

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