Anais do X Simpósio Internacional em Ciências Veterinárias (X SINCVET)

IN VITRO EFFICACY OF FUNGAL FORMULATIONS ON GASTROINTESTINAL HELMINTHS IN GOATS

Publicado em 22/05/2026 - ISBN: 978-65-272-2456-3

Link Todos os Trabalhos
Trabalho
Título do Trabalho
IN VITRO EFFICACY OF FUNGAL FORMULATIONS ON GASTROINTESTINAL HELMINTHS IN GOATS
Autores
  • Wendell Marcelo de Souza Perinotto
  • Beatriz do Nascimento Beserra
  • Juan Dario Puentes
  • Luís Otávio Guido de Souza
  • Tiago Marques dos Santos
  • Vânia Rita Elias Pinheiro Bittencourt
  • Isabele da Costa Angelo
  • Patricia Golo
  • JESSICA FIOROTTI DE PAULO
  • George Rego Albuquerque
Modalidade
Resumo Simples
Área temática
Helmintologia: sistemática, epidemiologia e controle
Data de Publicação
22/05/2026
País da Publicação
Brasil
Idioma da Publicação
pt-BR
Página do Trabalho
https://www.even3.com.br/anais/x-simposio-internacional-ciencias-veterinarias/1431703-in-vitro-efficacy-of-fungal-formulations-on-gastrointestinal-helminths-in-goats
ISBN
978-65-272-2456-3
Palavras-Chave
anthelmintic resistance, biological control, nematophagous fungi.
Resumo
With the advance of anthelmintic resistance, controlling gastrointestinal helminthiasis in small ruminants has become an increasing challenge. Given this scenario, sustainable alternatives, such as the use of nematophagous fungi, stand out as promising biocontrol strategies. The present study aimed to evaluate in vitro the efficacy of fungal formulations on immature stages of gastrointestinal helminths in goats. Fecal samples were collected directly from the rectal ampulla of naturally infected animals that had not received anthelminthic treatment for 60 days. The samples were homogenized and subjected to the McMaster technique, obtaining an average count of 1100 eggs per gram of feces (EPG). The action of the formulations was evaluated by quantitative coproculture. For this purpose, ten experimental groups were established, using the formulations BVET 93 (1.25 × 10⁷ conidia/g), BVET 94 (3.75 × 10⁶ conidia/g), BVET 99 (3.5 × 10⁶ conidia/g), and BVET 108 (7.5 × 10⁵ conidia/g), tested at concentrations of 1 g and 2 g. The species of fungus used in the formulations cannot yet be disclosed due to the confidentiality of the manufacturing company. A negative control containing only distilled water and a positive control composed of ivermectin at a concentration of 0.008 mg/mL were included. Each group consisted of ten experimental units. Efficacy was determined by the percentage reduction in larvae compared to the negative control. Data were analyzed by ANOVA, followed by Tukey's test at 5% significance. The results showed that, at a concentration of 1 g, formulations BVET 93, BVET 94, BVET 99, and BVET 108 had efficacies of 70.72%, 88.51%, 99.99%, and 100%, respectively. At a concentration of 2 g, these same formulations showed efficacies of 98.05%, 84.89%, 100%, and 100%. The positive control showed an efficacy of 98%. It is concluded that all formulations evaluated were able to significantly reduce the recovery of gastrointestinal helminth larvae from goats in in vitro tests, with BVET 99 and BVET 108 being the most promising, with high efficacy in both concentrations evaluated. The findings reinforce the potential of using nematophagous fungi as a sustainable alternative to chemical anthelmintics and suggest continuing evaluations in semi-field and field conditions to validate the practical application of these formulations in real production systems.
Título do Evento
X Simpósio Internacional em Ciências Veterinárias | X International Symposium in Veterinary Sciences
Cidade do Evento
Seropédica
Título dos Anais do Evento
Anais do X Simpósio Internacional em Ciências Veterinárias (X SINCVET)
Nome da Editora
Even3
Meio de Divulgação
Meio Digital

Como citar

PERINOTTO, Wendell Marcelo de Souza et al.. IN VITRO EFFICACY OF FUNGAL FORMULATIONS ON GASTROINTESTINAL HELMINTHS IN GOATS.. In: Anais do X Simpósio Internacional em Ciências Veterinárias (X SINCVET). Anais...Seropédica(RJ) UFRRJ, 2025. Disponível em: https//www.even3.com.br/anais/x-simposio-internacional-ciencias-veterinarias/1431703-IN-VITRO-EFFICACY-OF-FUNGAL-FORMULATIONS-ON-GASTROINTESTINAL-HELMINTHS-IN-GOATS. Acesso em: 06/11/2026

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