CANINE CUTANEOUS PLASMACYTOSIS - CASE REPORT

Melissa de Araújo Rodrigues; Stephanie Cardoso Da Silva; Victoria Caroline De Almeida Marques; Max Ferreira de Andrade

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Trabalho

Título do Trabalho

CANINE CUTANEOUS PLASMACYTOSIS - CASE REPORT

Autores

Melissa de Araújo Rodrigues
Stephanie Cardoso Da Silva
Victoria Caroline De Almeida Marques
Max Ferreira de Andrade

Modalidade

Resumo

Área temática

Outras áreas temáticas

Data de Publicação

10/03/2025

País da Publicação

Brasil

Idioma da Publicação

Inglês

Página do Trabalho

https://www.even3.com.br/anais/ix-simposio-internacional-em-ciencias-veterinarias-sincvet-ix-international-symposium-in-veterinary-sciences-isvs-499466/1033422-canine-cutaneous-plasmacytosis---case-report

ISBN

978-65-272-1246-1

Palavras-Chave

Histopathology, Immunohistochemistry, Myelogram, Plasma cells

Resumo

Cutaneous plasmacytosis is an uncommon syndrome in dogs and humans, characterized by multiple cutaneous nodules of plasmacytomas and the absence of multiple myeloma. In dogs, it can manifest as nodular, alopecic, circumscribed cutaneous lesions, pinkish in color, and often with an average diameter of 1-2 cm. Ears, lips, and limbs are common sites of presentation. Diagnosis is made through histopathological evaluation, which reveals the infiltration of plasma cells in the dermis. In cases of undifferentiated round cell neoplasms, immunohistochemistry is recommended to conclude the diagnosis and confirm their origin in plasma cells. Treatment generally involves the surgical removal of lesions. In cases of diffuse presentation or recurrences, the administration of corticosteroids and alkylating chemotherapeutic agents may be necessary. The objective of this paper is to report a case of cutaneous plasmacytosis in a 9-year-old Yorkshire terrier, with a clinical history of a nodule on the labial mucosa, in which the histopathological diagnosis was round cell neoplasm. After a year and a half, the patient returned for oncological care, presenting four cutaneous nodules located on the right front limb, head, tail, and mammary gland. Fine-needle aspiration of the nodules was then performed for cytological evaluation, with the diagnosis again suggesting round cell neoplasms, with mastocytoma as the main differential diagnosis. The patient was then referred for complementary imaging exams for staging. Thoracic radiography and abdominal ultrasound did not show significant clinical changes. Surgical treatment was implemented for the excision of the nodules and histopathological and immunohistochemical diagnosis. The final diagnosis was conclusive for plasmacytoma. The multiple and diffuse clinical presentation was indicative of cutaneous plasmacytosis. To rule out the hypothesis of multiple myeloma, a plasma cell neoplasm that occurs in the bone marrow, a radiographic study of the spine and long bones of the patient was performed to verify the occurrence of lytic bone lesions, and also a myelogram. In both exams, no results suggestive of multiple myeloma were found. Thus, the owners of the patient did not opt for the association of systemic treatments. It can be concluded that immunohistochemical evaluation is of great importance for the determination of the diagnosis of cutaneous plasmacytosis, as well as the myelogram for the differentiation of multiple myeloma. The literature is still scarce regarding the treatment of choice for cutaneous plasmacytosis.

Título do Evento: IX Simpósio Internacional em Ciências Veterinárias (SINCVET) / IX International Symposium in Veterinary Sciences (ISVS)
Título dos Anais do Evento: Anais do IX Simpósio Internacional em Ciências Veterinárias (SINCVET) / IX International Symposium in Veterinary Sciences (ISVS)
Nome da Editora: Even3
Meio de Divulgação: Meio Digital

Como citar

RODRIGUES, Melissa de Araújo et al.. CANINE CUTANEOUS PLASMACYTOSIS - CASE REPORT.. In: Anais do IX Simpósio Internacional em Ciências Veterinárias (SINCVET) / IX International Symposium in Veterinary Sciences (ISVS). Anais...Seropédica(RJ) UFRRJ, 2025. Disponível em: https//www.even3.com.br/anais/ix-simposio-internacional-em-ciencias-veterinarias-sincvet-ix-international-symposium-in-veterinary-sciences-isvs-499466/1033422-CANINE-CUTANEOUS-PLASMACYTOSIS---CASE-REPORT. Acesso em: 14/12/2025