PREVENTION OF EARLY-STAGE PRESSURE INJURIES IN HIGH-RISK PATIENTS USING PHOTOBIOMODULATION: A RANDOMIZED CONTROLLED CLINICAL TRIAL

ROBERTA OLIVEIRA DE JESUS TERTULIANO DE LIMA; Lara Jansiski Motta; Sandra Kalil Bussadori; Cinthya Cosme Gutierrez Duran; Kristianne Porta Santos Fernandes; Raquel Agnelli Mesquita-Ferrari; Anna Carolina Ratto Tempestini Horliana

Título del Trabajo

Autores

ROBERTA OLIVEIRA DE JESUS TERTULIANO DE LIMA
Lara Jansiski Motta
Sandra Kalil Bussadori
Cinthya Cosme Gutierrez Duran
Kristianne Porta Santos Fernandes
Raquel Agnelli Mesquita-Ferrari
Anna Carolina Ratto Tempestini Horliana

Modalidad

Protocolos de investigación

Área temática

Fisioterapia

Fecha de publicación

14/08/2026

País de publicación

Argentina | Argentina

Idioma de la Publicación

es-419

Página del Trabajo

https://www.even3.com.br/anais/ii-encuentro-biofotonica-597461/1251797-prevention-of-early-stage-pressure-injuries-in-high-risk-patients-using-photobiomodulation--a-randomized-control

ISBN

978-65-272-2678-9

Palabras Clave

photobiomodulation; pressure injury prevention; wound healing

Resumen

Pressure injuries (PIs) are frequent adverse events in hospitalized patients, ranking among the top causes of harm. Photobiomodulation (PBM) has shown benefits in wound healing, inflammation reduction, and tissue regeneration. While its use in advanced PIs is documented, application in early stages (Stages 1 and 2) is less explored. This study hypothesizes that early PBM intervention can prevent PI progression, reduce complications, and improve quality of life. This randomized controlled clinical trial will include 200 high-risk patients (Braden Scale < 9) with Stage 1 or 2 PIs. Participants will be randomly assigned to a PBM Group (n = 100), receiving irradiation in at-risk areas five times per week, or a Control Group (n = 100), receiving simulated PBM. Both groups will receive standard care, including wound cleansing, debridement, and dressings. The primary outcome is PI progression to more advanced stages. Secondary outcomes include time to PI development or regression, local pain intensity (Visual Analog Scale – VAS), wound healing score (PUSH scale), health-related quality of life (EQ-5D), number of dressing changes, adverse events, and patient satisfaction. Assessments will occur at baseline, week 1, and week 2 post-intervention. Data will be analyzed at a 5% significance level (p < 0.05) using an intention-to-treat approach. PI progression will be compared between groups with Fisher's exact or chi-square test. Continuous variables (VAS, PUSH, EQ-5D) will be tested for normality (Shapiro-Wilk) and compared with Student’s t-test or Mann-Whitney test. Intraindividual changes will be assessed with repeated measures ANOVA or Friedman test, according to data distribution.

Título del Evento: II Encuentro Latinoamericano de Investigación y Práctica en Biofotónica y I Seminario de Investigación de Posgrado en Salud
Ciudad del Evento: Buenos Aires
Título de las Actas del Evento: Actas II Encuentro Latinoamericano de Investigación y Práctica en Biofotónica y I Seminario de Investigación de Posgrado en Salud
Nombre de la Editora: Even3
Medio de Divulgación: Meio Digital

Como citar

LIMA, ROBERTA OLIVEIRA DE JESUS TERTULIANO DE et al.. PREVENTION OF EARLY-STAGE PRESSURE INJURIES IN HIGH-RISK PATIENTS USING PHOTOBIOMODULATION: A RANDOMIZED CONTROLLED CLINICAL TRIAL.. In: Actas II Encuentro Latinoamericano de Investigación y Práctica en Biofotónica y I Seminario de Investigación de Posgrado en Salud. Anais...Sao Paulo(SP) UNIMAIMONIDES, 2026. Disponible en: https//www.even3.com.br/anais/II-Encuentro-Biofotonica-597461/1251797-PREVENTION-OF-EARLY-STAGE-PRESSURE-INJURIES-IN-HIGH-RISK-PATIENTS-USING-PHOTOBIOMODULATION--A-RANDOMIZED-CONTROL. Acceso en: 21/08/2026