FROM STATISTICAL ASSOCIATION TO CLINICAL UTILITY: REFINING THE PROGNOSTIC CREDIBILITY OF DIFFUSION TENSOR IMAGING IN TRAUMATIC BRAIN INJURY

GUilherme BEzerra CArneiro; Luís Afonso Fernandes Gonçalves; Enzo Camargo Calabria Araújo; Lucas Enzo Bezerra Garcia Bahia; Matheus Mamed de Goes; Mariana Fernanda Cardoso Barros; Giovanna Soares Rodrigues

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Trabalho Completo

Resumo

Título do Trabalho

FROM STATISTICAL ASSOCIATION TO CLINICAL UTILITY: REFINING THE PROGNOSTIC CREDIBILITY OF DIFFUSION TENSOR IMAGING IN TRAUMATIC BRAIN INJURY

Autores

GUilherme BEzerra CArneiro
Luís Afonso Fernandes Gonçalves
Enzo Camargo Calabria Araújo
Lucas Enzo Bezerra Garcia Bahia
Matheus Mamed de Goes
Mariana Fernanda Cardoso Barros
Giovanna Soares Rodrigues

Modalidade

Resumo Expandido

Área temática

Temas livres em Medicina

Data de Publicação

24/07/2026

País da Publicação

Brasil

Idioma da Publicação

pt-BR

Página do Trabalho

https://www.even3.com.br/anais/congresso-internacional-em-saude-e-medicina-671651/1532285-from-statistical-association-to-clinical-utility--refining-the-prognostic-credibility-of-diffusion-tensor-imagin

ISBN

978-65-272-2634-5

Palavras-Chave

Prognosis; Diffusion tensor; Traumatic brain injury.

Resumo

Introduction: Diffusion tensor imaging (DTI) has emerged as a key tool for detecting microstructural white matter changes after traumatic brain injury (TBI), particularly in cases of subtle traumatic axonal injury not evident on conventional neuroimaging. Objective: This work critically analyzes the prognostic credibility of DTI in TBI, emphasizing the transition from statistical association to clinical utility. Methodology: A critical narrative literature review was conducted, focusing on meta-analyses, systematic reviews, scoping reviews, and longitudinal studies concerning DTI and TBI prognosis. Results and Discussion: Evidence consistently shows an association between DTI-derived metrics, especially fractional anisotropy and mean diffusivity, and functional, cognitive, and clinical severity outcomes. However, the strength of this association does not automatically translate into routine prognostic applicability. Significant barriers persist, including protocol heterogeneity, equipment variability, differences in post-trauma acquisition timing, diverse analytical methods, modest sample sizes, and limited external validation. Recent reviews indicate that DTI possesses robust biological plausibility and potential predictive value, especially when integrated into multimodal models incorporating clinical variables, severity scales, and other biomarkers. Conclusion: DTI has moved beyond being merely a promising experimental marker, but its prognostic credibility still requires methodological refinement to achieve broad clinical utility. The field's advancement depends less on demonstrating new associations and more on proving reproducibility, incremental value, and real impact on decision-making.

Título do Evento: Congresso Internacional em Saúde & Medicina
Título dos Anais do Evento: Anais do congresso internacional em saúde & medicina
Nome da Editora: Even3
Meio de Divulgação: Meio Digital

Como citar

CARNEIRO, GUilherme BEzerra et al.. FROM STATISTICAL ASSOCIATION TO CLINICAL UTILITY: REFINING THE PROGNOSTIC CREDIBILITY OF DIFFUSION TENSOR IMAGING IN TRAUMATIC BRAIN INJURY.. In: Anais do congresso internacional em saúde & medicina. Anais...Uberlândia(MG) Apex Eventos, 2026. Disponível em: https//www.even3.com.br/anais/congresso-internacional-em-saude-e-medicina-671651/1532285-FROM-STATISTICAL-ASSOCIATION-TO-CLINICAL-UTILITY--REFINING-THE-PROGNOSTIC-CREDIBILITY-OF-DIFFUSION-TENSOR-IMAGIN. Acesso em: 13/10/2026